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VIVISECTION-THE CUTTING EDGE OF MEDICAL SCIENCE!
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Azimuth



Joined: 19 Feb 2005
Posts: 318

Posted: Thu Sep 29, 2005 12:56 am    Post Subject: VIVISECTION-THE CUTTING EDGE OF MEDICAL SCIENCE!  

Biomedical research laboratory or Auschwitz?


This photo has been linked from this site:
http://www.novivisezione.org/mostra/index_en.htm

IF YOU VISIT THE ABOVE SITE PLEASE BE WARNED THAT IT CONTAINS OTHER GRAPHIC PICTURES DEPICTING ALLEGED ANIMAL EXPERIMENTATION AND MAY NOT BE SUITABLE FOR CHILDREN OR THE FAINT HEARTED.
(My warning)

What is Vivisection? The following is how it is described on the New Zealand Anti-Vivisection Organization website:

Quote:
"The term 'vivisection' is now used to apply to all types of experiments on living animals, whether or not cutting is done. So states the Encyclopedia Americana (International Edition 1974). And the large Merriam-Webster (1963): '... broadly, any form of animal experimentation, especially if considered to cause distress to the subject.' Thus the term also applies to experiments done with the administration of noxious substances, burns, electric or traumatic shocks, drawn-out deprivations of food and drink, psychological tortures leading to mental imbalance, and so forth. The term was employed in that sense by the physiologists of the last century who started this kind of 'medical research', and so it will be used by me. By 'vivisectionist' is usually meant every upholder of this method; by 'vivisector' someone who performs such experiments or participates in them."
- Hans Ruesch, Slaughter of the Innocent

Vivisection is an industry. Those sufficiently interested or concerned about animal experimentation, animal research, or animal trials (all euphemisms for vivisection) should be mindful of the gigantic financial enterprises operating under its name, on the premise that it is bona-fide. These businesses depend for their very survival on continued public acceptance of the belief that vivisection is authentic.
- Bette Overell, Animal Research Takes Lives - Humans and Animals Both Suffer

http://www.nzavs.org.nz/whatIs.html

There has been a bit of discussion relating to immunisations, vaccines, and vague references to animal testing in the threads, so I decided to have a look at how some of these vaccines and wonder drugs are tested prior to being released for human use.

All vaccines, drugs etc must first be tested on animals before being released for human medical applications. During testing animals are subjected to a barrage of sometimes cruel and inhumane tests causing severe pain and death. This is not specifically aimed at New Zealand but rather the wider global community, however there is no doubt whatsoever that New Zealand entities engage in and are complicit in such cruel and unnecessary animal experimentation and research.

Various cold and warm blooded invertebrate and vertebrate animals including frogs, mice, rats, cats, dogs, pigs, rabbits and primates etc are used in the testing. Some are purpose bred exclusively for laboratories, others such as frogs are captured from the wild. In some cases cats and dogs destined to be euthanized are taken from pounds.

In New Zealand the animal types most commonly used in experimentation are mice, sheep, cattle, and rats. Large numbers of possums and eels have also been used. To a lesser extent ferrets, stoats, feral cats, rabbits, hares, hedgehogs, pigs, chamois, ducks, weka, introduced birds, skinks, kereru, adelie penguins, eels and frogs have also been experimented on. The link below gives full details by number and species:
http://www.landcareresearch.co.nz/publications/annualreport_0001/supporting_info/animals%20in%20research.doc

The number of animals used in foreign medical research is vague as many countries such as the US are not required to keep records of cold blooded animals, rats and mice etc used or killed during research. Some estimate the figures at between 20 and 70 million annually in the US alone.

The number of warm-blooded vertebrate animals used each year in the US is approximately 28 million. Of that total, about 18 million animals are killed for research, compared with 2.51 million in England, 1.66 million in Canada, and 730,000 thousand in the Netherlands.
http://www.vivisectioninfo.org/

In New Zealand, statistics from the watchdog group National Animal Ethics Advisory Committee (NAEAC) show that 246,122 animals were “manipulated”(??) during 2004, with a long term average of 273,464. Whoa!

Let me spell that figure out; two hundred and seventy three thousand, four hundred and sixty four animals.

“Manipulation” you ask!

    “Manipulation” as defined in the Animal Welfare Act 1999:
    (1) In this Act, unless the context otherwise requires, the term “manipulation”, in relation to an animal, means, subject to subsections (2) and (3), interfering with the normal physiological, behavioural, or anatomical integrity of the animal by deliberately;
    (a) Subjecting it to a procedure which is unusual or abnormal when compared with that to which animals of that type would be subjected under normal management or practice and which involves –
    (i) Exposing the animal to any parasite, micro-organism, drug, chemical, biological product, radiation, electrical stimulation, or environmental condition; or
    (ii) Enforced activity, restraint, nutrition, or surgical intervention; or
    (b) Depriving the animal of usual care; –
    and “manipulating” has a corresponding meaning.
http://www.biosecurity.govt.nz/animal-welfare/naeac/annual-report/naeac-ar-04.pdf

So then the term “Manipulation” is nothing more that euphemism for vivisection!

In New Zealand, commercial organisation (89,076), universities (73,726) and Crown Research Institutes (60,572) are the largest “manipulators” of animals. Product, pesticide, genetic and biological testing high on the list of agents these animals are exposed to.

However, the “manipulators”, many using public money to conduct these cruel animal experiments refuse to release details of the exact nature of their experiments. Reportedly at least a fifth of the animals used experience severe to very severe suffering. Many thousands are killed. See Herald article 19.08.05:
http://www.nzherald.co.nz/topic/story.cfm?c_id=149&ObjectID=10341535

The NAEAC say it promotes the concepts of humane science and continues to pursue improvements by encouraging alternative non-animal testing when possible. This is supported by NAEAC’s promotion of the ‘Three Rs’, which encourage:

    replacement of live and conscious animals in experiments with unconscious or non-living alternatives at every opportunity;
    reduction in numbers to the minimum; and
    refinement of experimental techniques so as to minimise or eliminate any suffering involved
http://www.maf.govt.nz/mafnet/press/180805naeac.htm

However, that being said, animals are cheap, readily available, expendable, don’t complain, have no feelings(!) and aren’t required to sign medical release forms. They also can not report any “behind the closed door” breach of animal research ethics.

If drug testing driven animal experimentation is beneficial and so successful then why are the drugs that pharmaceutical companies peddle to the public of the world killing and causing us to become ill in epic proportions? See report as published in the Journal of the American Medical Association below:

Quote:
Adverse reactions to prescription and over-the-counter medicines kill more than 100,000 Americans and seriously injure an additional 2.1 million each year, researchers say.

Such reactions -- which do not include prescribing errors or drug abuse -- rank at least sixth among causes of death in the United States, behind heart disease, cancer, lung disease, strokes and accidents, according to a report published in this week's Journal of the American Medical Association. The report was based on an analysis of existing studies.

http://www.cnn.com/HEALTH/9804/14/drug.reaction/

As NZAV correctly indicate on their website, ”animals are different from humans and from each other, genetically, histologically, anatomically, physiologically, immunologically, emotionally, psychologically, sexually and socially.”

So then, why are all human medicines based on veterinary medical experimentation?

If animal medical experimentation is of questionable value why is it being conducted at all?

Surely this animal research is being conducted for the benefit of humanity, that Governments, pharmaceutical giants, chemical companies, universities, medical research institutes and mighty military warlords are driven by their overwhelming desire to rid our world of sickness and disease.

Surely the unimaginable profits, greed, power, lucrative contracts, deals, research grants, careers, notoriety and market dominance are just a mere by-product of their benevolence to us.

To Be Continued:

Or does the true drug testing begin in earnest, on the ideal “lab rats”, humans!!

Azimuth
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Azimuth



Joined: 19 Feb 2005
Posts: 318

Posted: Fri Sep 30, 2005 5:28 pm    Post Subject:  

“WHO ARE THE REAL LAB RATS?”

Animals are vastly dissimilar to humans, react to sickness and disease differently than humans and rarely suffer human diseases, so then why are human based medicines predominantly developed through animal experimentation and research?

How effective are these animal experiments and how safe are the drugs developed via this method?

From the lengthy article below, which I have reproduced in full, it is plainly evident that research and drugs developed for human use derived through animal experimentation do not work, that it is faulty, misleading, downright dangerous and lethal!

    FIFTY DISASTERS OF ANIMAL TESTING

    1. Benzene was not withdrawn from use as an industrial chemical despite clinical and epidemological evidence that exposure caused leukemia in humans, because manufacturer-supported tests failed to reproduce leukemia in mice.[1]

    2. Smoking was thought to be non-carcinogenic because smoking-related cancer is difficult to reproduce in lab animals. Consequently many continued to smoke and to die from cancer.[2]

    3. Animal experiments on rats, hamsters, guinea pigs, mice, monkeys, and baboons revealed no link between glass fibers and cancer. Not until 1991, due to human studies, did OSHA label it carcinogenic.[3][4][5]

    4. Though arsenic was a known human carcinogen for decades, scientists still found little evidence in animals to support the conclusion as late as 1977.[6] This was the accepted view until it was eventually possible to produce in animals.[7][8][9]

    5. Many humans continued to be exposed to asbestos and die because scientists could not reproduce the cancer in laboratory animals.

    6. Pacemakers and heart valves were delayed in development because of physiological differences between animals on which they were designed and humans for whom they were intended.

    7. Animal models of heart disease failed to show that a high cholesterol/high fat diet increases the risk of coronary artery disease. Instead of changing their eating habits to prevent the disease, people continued their lifestyles with a false sense of security.

    8. Patients received medications that were harmful and/or ineffective due to animal models of stroke.

    9. Animal studies predicted that beta-blockers would not lower blood pressure. This withheld their development.[10][11][12] Even animal experimenters admitted the failure of animal models of hypertension in this regard, but in the meantime, there were thousands more stroke victims.

    10. Surgeons thought they had perfected radial keratotomy, surgery performed to enable better vision without glasses, on rabbits, but the procedure blinded the first human patients (The rabbit cornea is able to regenerate on the underside, whereas the human cornea can only regenerate on the surface). Surgery is now performed only on the surface.

    11. Combined heart lung transplants were supposedly 'perfected' on animals, but the first 3 human patients all died within 23 days.[13] Of the 28 patients operated on between 1981 and 1985, 8 died peri-operatively, and 10 developed obliterative bronchiolitis, a lung complication that the dogs on whom experiments had been conducted did not develop. Of those 10 humans who developed obliterative bronchiolitis, 4 died and 3 never breathed again without the aid of a respirator. Obliterative bronchiolitis turned out to be the most important risk of the operation.[14]

    12. Cyclosporin A inhibits organ rejection, and its development was a watershed in the success of transplant operations. Had human evidence not overwhelmed unpromising evidence from animals, it would never have been released.[15]

    13. Animal experiments failed to predict the kidney toxicity of the general anesthetic methoxyflurane. Many people lost all kidney function.

    14. Animal experiments delayed the use of muscle relaxants during general anesthesia.

    15. Research on animals failed to reveal bacteria as a cause of ulcers and delayed treating ulcers with antibiotics.

    16. More than half of the 198 new medications released between 1976 and 1985 were either withdrawn or relabeled secondary to severe unpredicted side effects.[16] These side effects included complications such as lethal dysrhythmias, heart attacks, kidney failure, seizures, respiratory arrest, liver failure, and stroke, among others.

    17. Flosint, an arthritis medication, was tested on rats, monkeys and dogs; all tolerated the medication well. However, in humans it caused deaths.

    18. Zelmid, an antidepressant, was tested on rats and dogs without incident, but it caused severe neurological problems in humans.

    19. Nomifensine, another antidepressant, was linked to kidney and liver failure, anemia, and death in humans. And yet animal testing had indicated that it could be used without side-effects occurring.

    20. Amrinone, a medication used for heart failure, was tested on numerous animals and was released without any trepidation. But humans developed thrombocytopenia, a lack of the type of blood cells that are needed for clotting.

    21. Fialuridine, an antiviral medication, caused liver damage in 7 out of 15 people. 5 eventually died and 2 more needed liver transplants.[17] And yet it had worked well in woodchucks.[18][19]

    22. Clioquinol, an antidiarrheal, passed tests in rats, cats, dogs and rabbits. But it had to be withdrawn all over the world in 1982 after it was found to cause blindness and paralysis in humans.

    23. Eraldin, a medication for heart disease, caused deaths and blindness in humans despite the fact that no untoward effects could be shown in animals. When introduced, scientists said it noted for the thoroughness of the toxicity studies on animals. Afterwards, scientists were unable to reproduce these results in animals.[20]

    24. Opren, an arthritis medication, killed 61 people. Over 3500 cases of severe reactions have been documented. Opren had been tested on monkeys and other animals without problems.

    25. Zomax, another arthritis drug, was responsible for the death of 14 people and causing suffering to many more.

    26. The dose of isoproterenol, a medication used to treat asthma, was calculated in animals. Unfortunately, it was much too toxic for humans. 3500 asthmatics died in Great Britain alone due to overdose. It is still difficult to reproduce these results in animals.[21][22][23][24][25][26]

    27. Methysergide, a medication used to treat headaches, led to retroperitoneal fibrosis, or severe scarring of the heart, kidneys, and blood vessels in the abdomen.[27] Scientists have been unable to reproduce this in animals.[28]

    28. Suprofen, an arthritis drug, was withdrawn from the market when patients suffered kidney toxicity. Prior to its release researchers had this to say about the animal tests: '...excellent safety profile. No...cardiac, renal, or CNS [central nervous system] effects in any species'.[29][30]

    29. Surgam, another arthritis drug, was designed to have a stomach protection factor that would prevent stomach ulcers, a common side effect of many arthritis drugs. Although promising in lab animal tests, ulcers occurred in human trials.[31][32]

    30. Selacryn, a diuretic, was thoroughly tested on animals, but it was withdrawn in 1979 after 24 people died from drug induced liver failure.[33][34]

    31. Perhexiline, a heart medication, was withdrawn when it produced liver failure which had not been predicted by animal testing. Even when the particular type of liver failure was known, it could not be induced in animals.[35] 32. Domperidone, designed as a treatment for nausea and vomiting, made human hearts beat irregularly and had to be withdrawn. Scientists were unable to reproduce this in dogs even with 70 times the normal dose.[36][37]

    33. Mitoxantrone, a treatment for cancer produced heart failure in humans. It was extensively tested on dogs, which did not manifest this effect.[38][39]

    34. Carbenoxalone was supposed to prevent formation of gastric ulcers but caused people to retain water to the point of heart failure. After vivisectors knew what it did to humans they tested it on rats, mice, monkeys, rabbits, but could not reproducing this effect.[40][41]

    35. Clindamycin, an antibiotic, causes a bowel condition called pseudomenbraneous colitis. And yet it was tested in rats and dogs every day for a year; moreover, they were able to tolerate doses ten times greater than humans are able to.[42][43][44]

    36. Animal experiments did not support the efficacy of valium-type drugs during development or subsequently.[45][46]

    37. The pharmaceutical companies Pharmacia and Upjohn discontinued clinical tests of its Linomide (roquinimex) tablets for the treatment of multiple sclerosis after several patients suffered heart attacks. Of 1,200 patients, 8 suffered heart attacks as a result of taking the medication. Animal experiments had not predicted this.

    38. Cylert (pemoline), a medication used to treat Attention Deficit Hyperactive Disorder, caused liver failure in 13 children. Eleven either died or required a liver transplant.

    39. Eldepryl (selegiline), a medication used to treat Parkinson's disease, was found to induce very high blood pressure. This side effect has not been seen in animals.

    40. The diet drug combination of fenfluramine and dexfenfluramine was linked to heart valve abnormalities and withdrawn although animal studies had never revealed heart abnormalities.[47]

    41. The diabetes medication troglitazone, better known as Rezulin, was tested on animals without significant problems, but caused liver damage in humans. The manufacturer admitted that at least one patient had died and another had to undergo a liver transplant as a result.[48]

    42. The plant digitalis has been used for centuries to treat heart disorders. However, clinical trials of the digitalis-derived drug were delayed because it caused high blood pressure in animals. Fortunately, human evidence overrode and as a result, digoxin, an analogue of digitalis, has saved countless lives. Many more people could have survived had the animal testing been ignored and digitalis been released earlier.[49][50][51][52]

    43. FK 506, now called Tacrolimus, is an anti-rejection agent that was almost abandoned before proceeding to clinical trials due to severe toxicity in animals.[53][54] Animal studies suggested that the combination of FK 506 with cyclosporin might prove more useful.[55] In fact, just the opposite proved true in humans.[56]

    44. Animal experiments suggested that corticosteroids would help septic shock, a severe bacterial infection of the blood.[57][58] However, humans reacted differently. This treatment increased the death rate in cases of septic shock.[59]

    45. Despite the ineffectiveness of penicillin in rabbits, Alexander Fleming used the antibiotic on a very sick patient since he had nothing else to try. Fortunately, Fleming's initial tests were not on guinea pigs or hamsters because it kills them. Howard Florey, the Nobel Prize winner credited with co-discovering and manufacturing penicillin, stated: 'How fortunate we didn't have these animal tests in the 1940s, for penicillin would probably never been granted a license, and possibly the whole field of antibiotics might never have been realized'.

    46. Fluoride, a cavity preventative, was initially withheld because it caused cancer in rats.[60][61][62]

    47. The notoriously dangerous drugs thalidomide and DES were tested in animals and released for human usage. Tens of thousands suffered and/or died as a result.

    48. Animal experiments misinformed researchers about how rapidly HIV replicates. Based on this false information, patients did not receive prompt therapies and their lives were shortened.

    49. Animal-based research delayed the development of the polio vaccine, according to Dr. Albert Sabin, its inventor. The first rabies and polio vaccines worked well on animals but crippled or killed the people who tried them.

    50. Researchers who work with animals have succumbed to illness and death due to exposure to diseases that while harmless to the animal host (such as Hepatitis B) are potentially or actually deadly for humans.

    Endnote.
    Time, money, and resources devoted to these experiments could have gone to human-based research. Clinical studies, in vitro research, autopsies, post-marketing drug surveillance, computer modeling, epidemiology, and genetic research pose no hazard to humans and provide accurate results.
    Importantly, animal experiments have exhausted resources that could have been dedicated to educating the public about health hazards and health maintenance, therein diminishing the incidence of disease that require treatment.

Here is the link to the article and references.
http://www.curedisease.com/Harms.html

So who benefits from animal research?
What are the alternatives to animal testing?


Azimuth
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Carus



Joined: 22 Feb 2004
Posts: 352
Location: Auckland

Posted: Sun Oct 02, 2005 4:56 pm    Post Subject:  

Hello Azimuth,

I wasn't brave enough to look at more pictures but my partner had a look and I got a verbal description of some of the stuff there. Quite a can of worms this subject isn't it :!:

After my post in reply to Hiero's Tamiflu subject (https://www.mysteriousnewzealand.co.nz/forums/viewtopic.php?t=340 ) I recalled that the vaccine supplied to NZ for the current Meningococcal 'epidemic' was by Chiron Corp. They were banned from supplying a flu vaccine to the USA in October 2004 for 3 months because it was found to be contaminated with bacteria. On looking further into the activities of this company I found that they are associated with Huntingdon Life Sciences and were granted an injunction in Great Britain against animal rights activists protesting around both company property and employees homes.

http://news.bbc.co.uk/2/hi/uk_news/england/london/3473217.stm

Huntington seems to be the subject of much protesting by animal activists for their cruelty to animals and there is a web site dedicated specifically to it:

http://www.shac.net/

Not only that, Chiron produced a meningitis C vaccine in the UK around 4 years ago which caused several deaths that were covered up by the health authorities "for fear of panicking parents".

We are looking more like a flock of sheep to the slaughter over this vaccine than ever. This from an article titled: Chiron: Vaccine License Suspended - Doubts Over Flu And Meningococcal Vaccines

Quote:
But Chiron Corporation is not only supplying flu vaccines. The company is currently involved in a 200 million $ contract with the New Zealand health authorities to supply a meningococcal vaccine for a mass vaccination program expected to cover more than a million children in that country. The vaccine is highly experimental and next to nothing is known about its side effects, but NZ health authorities are telling the population "not to worry". Investigative journalist Jonathan Eisen has done a remarkable job documenting the New Zealand meningococcal vaccine's potentially hazardous profile citing Chiron's own data sheets. His article is contained in a special issue of "What Your Doctor Will Never Tell You", which can be downloaded in PDF format here...


Also in the article reference is made to Dr Mike Godfrey's article Meningitis – or Scurvy? which particularly relates to NZ:

Quote:
It would appear thus that meningococcal disease is both eminently preventable and even curable by simply supplying sufficient amounts vitamin C, a nutrient which is of great importance for health but which human bodies cannot manufacture, to those suffering from the infection or who might be at risk of contracting it.

Godfrey also mentions in his article that the "epidemic" apeared to be already well on its way out and that the number of cases had been sharply reduced in the years prior to the all-out vaccination drive of the New Zealand health authorities.


The article (quoted above) has a wealth of other information and links as well (if you've got a few hours :lol: ). See it here:

http://www.newmediaexplorer.org/sepp/2004/10/06/chiron_vaccine_license_suspended_doubts_over_flu_and_meningococcal_vaccines.htm
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